Barbara Crampton was born on December 27, 1958 in Levittown, New York. Growing up in Vermont, she spent the majority of her childhood summers travelling the country with a roadside carnival that her father worked for. Crampton began acting in school plays in seventh grade and subsequently studied drama in high school. She earned a BA in Theater Arts from Castleton State College.
Barbara achieved enduring cult popularity as college coed Megan Halsey in Stuart Gordon’s Re-Animator (1985) and, after making a splash in the horror genre, successively starred in From Beyond (1986), Chopping Mall (1986), Puppetmaster (1989), and Castle Freak (1995), among others.